By Leaf Huang, Dexi Liu, Ernst Wagner
The box of genetics is swiftly evolving, and new clinical breakthroughs are taking place because of advances in our wisdom of genetics. Advances in Genetics continuously publishes vital studies of the broadest curiosity to geneticists and their colleagues in affiliated disciplines.
- Includes equipment for checking out with moral, criminal, and social implications
- Critically analyzes destiny directions
- Written and edited by means of famous leaders within the field
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Extra info for Nonviral vectors for gene therapy : physical methods and medical translation
Et al. (2003). Femtosecond infrared laser-an efﬁcient and safe in vivo gene delivery system for prolonged expression. Molecular Therapy, 8, 342–350. , et al. (2007). Femtosecond laser: a new intradermal DNA delivery method for efﬁcient, long-term gene expression and genetic immunization. FASEB Journal: Ofﬁcial Publication of the Federation of American Societies for Experimental Biology, 21, 3522–3533. , & Wolff, J. A. (1999). High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA.
MICRORNA-LOADED BLs MicroRNAs (miRNAs) are involved in biological functions, and their dysregulation often leads to human diseases (McManus & Sharp, 2002). Recently, a large number of miRNAs were identiﬁed as key targets for therapeutic intervention. However, a vehicle for efﬁciently delivering therapeutic RNA to its target tissue is required for miRNA-based therapeutics (Zhang, Wang, & Gemeinhart, 2013). , 2008). , 2013). The amount of miRNA bound to the BLs increased in the presence of cationic lipid.
Journal of Controlled Release: Ofﬁcial Journal of the Controlled Release Society, 133, 198–205. , et al. (2008). Effective anti-tumor activity of oxaliplatin encapsulated in transferrin-PEG-liposome. International Journal of Pharmaceutics, 346, 143–150. , et al. (2007). Gene delivery by combination of novel liposomal bubbles with perﬂuoropropane and ultrasound. Journal of Controlled Release: Ofﬁcial Journal of the Controlled Release Society, 117, 130–136. , & Maruyama, K. (2007). Effective gene delivery with liposomal bubbles and ultrasound as novel non-viral system.