Download Nonviral vectors for gene therapy : physical methods and by Leaf Huang, Dexi Liu, Ernst Wagner PDF

By Leaf Huang, Dexi Liu, Ernst Wagner

The box of genetics is swiftly evolving, and new clinical breakthroughs are taking place because of advances in our wisdom of genetics. Advances in Genetics continuously publishes vital studies of the broadest curiosity to geneticists and their colleagues in affiliated disciplines.

  • Includes equipment for checking out with moral, criminal, and social implications
  • Critically analyzes destiny directions
  • Written and edited by means of famous leaders within the field

Show description

Read or Download Nonviral vectors for gene therapy : physical methods and medical translation PDF

Similar basic science books

Inorganic biochemistry of iron metabolism: from molecular mechanisms to clinical consequences

Iron is of basic value for the expansion, improvement and health of just about all dwelling organisms. a number of organic platforms were built for the uptake, utilisation, garage and homeostasis of iron in microbes, crops and mammals. e. g. either iron deficiency and iron overload are came across greatly in guy: the intimate hyperlinks among iron and oxidative pressure are linked to a variety of pathologies; iron has a good confirmed position in infections via quite a lot of microorganisms and parasites; there's a shut hyperlink among iron requisites and mobile department with implications for cancers and different metals equivalent to copper and zinc are heavily associated with iron metabolism.

Biostatistics and Microbiology: A Survival Manual

This "nuts and bolts" booklet offers a condensation of biostatistical tools that utilized microbiology researchers have to practice facts analyses. in response to the author’s greater than twenty years of utilized study and instructing event, it truly is offered in a straight-forward demeanour, appropriate by means of working towards microbiologists with minimum backgrounds in arithmetic.

The Cytokine Factsbook and Webfacts

Thoroughly revised and improved, this moment variation of The Cytokine FactsBook is the main updated reference handbook on hand for all present well-characterized interleukins, cytokines, and their receptors. an extra fifty two cytokines are integrated, doubling the variety of entries from the former version.

Statistics in Human Genetics and Molecular Biology

Concentrating on the jobs of alternative segments of DNA, records in Human Genetics and Molecular Biology offers a simple realizing of difficulties bobbing up within the research of genetics and genomics. It provides statistical functions in genetic mapping, DNA/protein series alignment, and analyses of gene expression information from microarray experiments.

Extra info for Nonviral vectors for gene therapy : physical methods and medical translation

Sample text

Et al. (2003). Femtosecond infrared laser-an efficient and safe in vivo gene delivery system for prolonged expression. Molecular Therapy, 8, 342–350. , et al. (2007). Femtosecond laser: a new intradermal DNA delivery method for efficient, long-term gene expression and genetic immunization. FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology, 21, 3522–3533. , & Wolff, J. A. (1999). High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA.

MICRORNA-LOADED BLs MicroRNAs (miRNAs) are involved in biological functions, and their dysregulation often leads to human diseases (McManus & Sharp, 2002). Recently, a large number of miRNAs were identified as key targets for therapeutic intervention. However, a vehicle for efficiently delivering therapeutic RNA to its target tissue is required for miRNA-based therapeutics (Zhang, Wang, & Gemeinhart, 2013). , 2008). , 2013). The amount of miRNA bound to the BLs increased in the presence of cationic lipid.

Journal of Controlled Release: Official Journal of the Controlled Release Society, 133, 198–205. , et al. (2008). Effective anti-tumor activity of oxaliplatin encapsulated in transferrin-PEG-liposome. International Journal of Pharmaceutics, 346, 143–150. , et al. (2007). Gene delivery by combination of novel liposomal bubbles with perfluoropropane and ultrasound. Journal of Controlled Release: Official Journal of the Controlled Release Society, 117, 130–136. , & Maruyama, K. (2007). Effective gene delivery with liposomal bubbles and ultrasound as novel non-viral system.

Download PDF sample

Rated 4.99 of 5 – based on 12 votes