Download Cryptorchidism: Ultrastructure of Normal and Cryptorchid by F. Hadziselimovic PDF

By F. Hadziselimovic

Cytological suggestions have tremendously enhanced within the final two decades, mostly due to additional improvement of the microscope. Electron microscopy, specifically, has spread out nice clients for the research of telephone morphology, whereas the improve­ ment of radio-immuno-assay has introduced nice growth in endocrinology. The applica­ tion of those ideas, that are complementary to one another and supply jointly aiding proof, is the topic of this monograph. The paintings is split into elements. the 1st bargains with the ultrastructure of ordinary testicular improvement, describing 4 major components of the testicle - the germ cells, the Sertoli cells, the peri tubular connective tissue and the Leydig phone- with info in their person improvement. To make the electron micrographs extra simply comprehensible, diagrams were used to provide an explanation for crucial issues. the second one half bargains with cryptorchid testicles, together with the first and sec­ ondary alterations concerned and morphometric stories of the secondary adjustments. the importance of those ultrastructural observations for the remedy of cryptorchidism is emphasised. because of radio-immuno-assay the extent of testosterone in cryp­ torchid mice was firm and comparisons drawn among the ultrastructural adjustments in cryptorchidism in mouse and guy. The experimental reviews served as a foundation for the speculation that, most likely, a congenital disturbance of the hy­ pothalamo-hypophyso-gonadal axis is liable for cryptorchidism. i am hoping that this monograph will give a contribution in the direction of a greater figuring out of ordinary and cryptorchid testicular improvement and of the etiology of cryptorchidism.

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Additional resources for Cryptorchidism: Ultrastructure of Normal and Cryptorchid Testis Development

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The nucleolus is peripherally situated and in contact with the nuclear membrane. The smooth endoplasmic reticulum occurs in vesicular form and fills almost the entire cell. A few mitochondria of the crista type are visible_ The lipoid droplet content is much reduced. Ribosomes and glycogen granules are occasionally visible in the cytoplasm. Very rarely microbodies can be seen, generally on the cell periphery. No Reinecke's crystalloid is discernible. d) Puberty (Fig. 32) With the onset of puberty, the Leydig cells become bigger and more common in the interstitium.

The contractions occur at intervals of thirty to fortyfive seconds, the tubular wall contracting with an amplitude of up to 10 JJ.. The contractions seem to move in the direction of the rete testis. Also the isolated tunica propria, i. e. without the tubulus seminiferus contents, has the capacity to contract (Clermont, 1960). Setschell studied in detail a further function of the peri tubular structure, namely that of metabolic transport regulator. He distinguished an active and a passive transport, dividing substances into three groups, according to flow rate.

5 ng per testis and in E2 B, i. u. 001). There is no significant difference between the mean testis weight of control mice (129 g) and that of E2 B mice (126 g). Discussion The most widely held theory of. testicular development from birth to puberty was that ofCharny et al. (1952), who distinguished three phases in the development of the testicle: the static phase, the growth phase and the maturation phase. Stadtler (1975) rejected the theory of development in phases, on the grounds that the seminiferous tubule showed a continuous increase in diameter and in the number of spermatogonia up to the eleventh year.

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