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By John DeLuca

As much as 85-95% of continual Fatigue Syndrome sufferers whinge of cognitive difficulties, and scientific neuropsychologists play a key function of their evaluate and therapy. This specified factor addresses a wide array of matters that confront them. It provides new study on CFS around the spectrum of clinical and medical inquiry, together with psychopathology, cognitive and cerebral functioning, genetics and immunology, and incapacity and outcome.

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DeCarli, C. , Gillette, J. , McIntosh, A. , Haxby, J. , Schapiro, M. , Rapoport, S. , & Horwitz, B. (1993). Volumetric magnetic resonance imaging in men with dementia of the Alzheimer type: Correlations with disease severity. Biological Psychiatry, 34, 612–621. Natelson, B. , Cohen, J. -J. (1993). A controlled study of brain magnetic resonance imaging in patients with the chronic fatigue syndrome. Journal of Neurological Sciences, 120, 213–217. , & Marsh, L. (1995). Structural brain imaging in schizophrenia.

Finally, psychiatric status, age, and between-test duration were significant predictors of outcome. Overall, the prognosis for CFS appears to be poor, as the majority of participants remained functionally impaired over time and were unemployed at follow-up, despite the noted improvements. Key words: chronic fatigue, neuropsychological assessment, follow-up Although numerous cross-sectional studies document the extent and nature of cognitive impairment, psychological distress, disability, and unemployment in chronic fatigue syndrome (CFS), it remains unclear how these factors change over time (Tiersky, Johnson, Lange, Natelson, & DeLuca, 1997; Wessely, Hotopf, & Sharpe, 1998).

1995). Brainstem perfusion is impaired in chronic fatigue syndrome. Quarterly Journal of Medicine, 88, 767–773. , & Natelson, B. H. (1995). Neuropsychological impairments in chronic fatigue syndrome, multiple sclerosis, and depression. Journal of Neurology, Neurosurgery, and Psychiatry, 58, 38–43. , Johnson, S. , Ellis, S. , & Natelson, B. H. (1997). Cognitive functioning is impaired in patients with chronic fatigue syndrome devoid of psychiatric disease. Journal of Neurology, Neurosurgery, and Psychiatry, 62, 151–155.

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