Download Cellular Signaling and Innate Immune Responses to RNA Virus by Allan R. Brasier, Adolfo García-Sastre, Stanley M. Lemon PDF

By Allan R. Brasier, Adolfo García-Sastre, Stanley M. Lemon

A accomplished survey of the latest discoveries during this field.

  • Provides a platform of information that would result in the improvement of greater tools for controlling the unfold of RNA viruses or enhancing their affliction course.
  • Synthesizes fresh findings during this fast-moving box whereas additionally reviewing authorised wisdom.
  • Focuses at the antiviral signaling pathways within the host, together with particular development attractiveness receptors and the way those mobile alarms sign the innate immune reaction.
  • Examines the ways that particular significant RNA virus households engage with, turn on, and elude those signaling pathways and responses.

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Cellular Signaling and Innate Immune Responses to RNA Virus Infections

A entire survey of the newest discoveries during this box. presents a platform of data that might bring about the advance of more advantageous equipment for controlling the unfold of RNA viruses or editing their sickness path. Synthesizes fresh findings during this fast-moving box whereas additionally reviewing authorised wisdom.

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Additional info for Cellular Signaling and Innate Immune Responses to RNA Virus Infections

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S. Sato, K. Mori, K. Hoshino, O. Takeuchi, K. Takeda, and S. Akira. 2002. Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Tolllike receptor signaling. J. Immunol. 169:6668–6672. 122. , M. Kikuchi, T. Natsukawa, N. Shinobu, T. Imaizumi, M. Miyagishi, K. Taira, S. Akira, and T. Fujita. 2004. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5:730–737.

S. Kobayashi, L. H. Glimcher, and H. Cantor. 2006. Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells. Nat. Immunol. 7:498–506. , R. Romieu-Mourez, D. Goubau, N. Grandvaux, T. Mesplede, I. Julkunen, A. Nardin, M. Salcedo, and J. Hiscott. 2007. Involvement of TBK1 and IKKepsilon in lipopolysaccharide-induced activation of the interferon response in primary human macrophages. Eur. J. Immunol. 37:528–539. Song, Y. , K. Y. Jen, V. Soni, E. Kieff, and E.

Takeuchi, S. Sato, M. Yamamoto, T. Kaisho, H. Sanjo, T. Kawai, K. Hoshino, K. Takeda, and S. Akira. 2004. The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection. J. Exp. Med. 199:1641–1650. 41. , X. Du, P. Georgel, E. Janssen, K. Tabeta, S. O. Kim, J. Goode, P. Lin, N. Mann, S. Mudd, K. Crozat, S. Sovath, J. Han, and B. Beutler. 2003. Identification of Lps2 as a key transducer of MyD88-independent TIR signalling. Nature 424:743–748.

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